Product Summary

Bonegrafix products will contain bioactive substances to achieve ideal graft attributes.  These products fall into two categories:  (1) solid bone blocks for bone replacement and (2) small powdered or granular substances (with and without inclusion of a cement) for filling defects or holes in bone or holding bone together during healing.

Bonegrafix will produce bone blocks in standard shapes (e.g., cube, rectangle, or wedge) and custom sizes shaped by the clinician.  Using information obtained from a patient’s anatomical CT scan, the clinician will be able to select the precise skeletal area where bone addition and/or replacement is required.  Bonegrafix can produce a precise bone replacement with optimal surface contact area for maximum tissue regeneration.

In a series of proof-of-concept studies, Bonegrafix has demonstrated production of a bone replacement based on CT data as well as a custom design using computer-aided-design (CAD).  This feature would be especially important for plastic or maxillo-facial surgeons performing cranio-facial reconstruction.  Additional studies indicate significant advantages such as more rapid new bone formation with greater volume when compared to available products.

Unique to Bonegrafix technology is ambient room temperature processing.  As the Company’s manufacturing process does not degrade heat sensitive biologics and/or drugs, it permits direct inclusion to promote rapid bone healing and new bone formation.